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16-Channel Extracellular Differential AC Amplifier Model 3500

The Model 3500 includes:

  • USB Cable: Type A to Type B
  • 16 40-inch input cables
  • Control software
  • Operator's manual
  • Rack mount hardware
  • Power supply

Please note that A-M Systems instruments are not approved for use with human subjects in either a clinical or research environment.

Catalog # Description Price Quantity
950000 Model 3500 16-Channel AC Amplifier, 110 V, 60 Hz

950005 Model 3500 16-Channel AC Amplifier, 220 V, 50 Hz

749935 Extended Warranty, 2 Year, Model 3500

951000 Model 3500 Breakout Board, Safelead

952000 Model 3500, Input Cables, Standard, 40"

950500 Model 3500/3600 Cable, Ganged Output, D25 to Open, 6' long

961500 Headstage Interface Adapter, Model 3500

955000 SciWorks Data Acquisition System, with Software and 16-Channel USB Acquisition Box
Contact Us to Order
956000 SciWorks Data Acquisition System, With Software and 32-Channel USB Acquisition Box
Contact Us to Order


A-M Systems is proud to introduce our new Model 3500 16-Channel Extracellular Differential AC Amplifier.

In response to many inquiries for a larger version of our popular Model 1700 4-Channel Differential AC Amplifier, we have developed this unit. The Model 3500 has 16 independent channels, a front panel touch screen, computer control capabilities and a built-in calibrator. In addition, users can quickly monitor on an external oscilloscope the activity on any two channels.

Multiple instruments will be controllable by a single computer program, enabling the setting of critical parameters on as many channels as you need.

Compared to the Model 1700, the Model 3500 has:
  • More gain settings and increased gain range
  • More high pass filter settings and increased high pass range
  • More low pass filter settings and increased low pass range
  • TTL Control of instrument mode
  • Twin stimulation busses to pass current
  • Channel Monitors
  • Built-In Calibration signal
  • Common Reference Bus
  • Blanking
  • PC control capability
  • MATLAB® and LabVIEW SDK and drivers available
  • Less rack space utilized for 16 channels

Need a Data Acquisition and Analysis System? 
A-M Systems now offers a complete Data Acquisition and Analysis system, including software, A/D card, and input/output patch panel. Made by Datawave Technologies, this system is the complete solution to your acquisition, storage, and analysis needs. Click here for more information.

Purchase of the Data Acquisition and Data Analysis System requires bundling with an A-M Systems Amplifier.

Need a Headstage?
Planning on recording units with electrode impedances over 1 meg? Learn about our Model 3600 16-channel Amplifier With Headstage.



  • Voltage, fB = 10 Hz-10 kHz, typical: 1.0 µV, p-p
Offset Voltage
  • Average Drift , typical: ±4.0 µV/Deg C
  • Average Drift , maximum: ±30.0 µV/Deg C
Bias Current
  • Initial Bias Current, maximum: ±0.4 nA
Offset Current
  • Input Offset Current, maximum: ±0.4 nA
Input Impedance
  • 1012 Ω || 4 pF
Inter-channel Crosstalk
  • 100 dB at 1 kHz
Input Voltage Size
  • VDC: 1 Volt
  • VAC: Gain / 10 Volts
  • Commmon Mode Rejection (CMR): 100 dB
Rated Output
  • Voltage Output: ±11 V
  • Output Resistance: >100 Ωs
Low Cut-Off Filter
  • Cut-Off Frequencies: 0.3, 1.0, 3.0, 10.0, 30.0, 100, 300, 500 Hz
  • Cut-Off Rate: 40dB/decade
High Cut-Off Filter
  • Cut-Off Frequencies: 0.1, 0.3, 0.5, 1.0, 3.0, 5.0, 10.0, 20.0 kHz
  • Cut-Off Rate: 40 B/decade
Notch Filter
  • Center Frequency: 50 Hz or 60 Hz
  • Rejection: >35 dB
  • 13 values from x2 to x20,000

Touch Screen

Settings of the various features of the amplifier can be set either by the touchscreen LCD on the unit itself, or by a PC compatible computer program.

Below are screen captures of a few of the on-board control screens.

The CHANNEL EDIT SCREEN is used to edit the parameters of the amplifier channels. The top line of the CHANNEL EDIT SCREEN (as well as all other screens) is the TOOLBAR, which contains navigation icons that allow the user to navigate to key screens. The horizontal SINGLE CHANNEL SELECT LIST selects the channel whose current settings are displayed in the vertical parameter lists (High Pass, Low Pass, Gain, Notch, Reference, and Mode).

Pressing any value displayed in any list will highlight that value, and will immediately set that channel''s parameter to the selected value. Thus, this is the equivalent action of turning a dial or a knob on traditional amplifiers.

If desired, it is possible to copy the parameters of this selected channel to any or all of the remaining channels. Simply select which channels you would like the parameters copied to by highlighting the channel numbers in the double rows of the MULTICHANNEL SELECT LIST at the bottom of the EDIT SCREEN. Pressing COPY will then transfer the channel parameters to the selected channels.

Pressing 16 at the top of any screen will display the 16-CHANNEL VIEW screen. The first 16-Channel view displays the most commonly changed parameters (High Pass Filter, Low Pass Filter, and Gain settings) of all 16 channels. Pressing the arrow in the lower right-hand corner will switch the display to the other parameters (Notch, Common Reference, and Mode).

Options on the MAIN MENU screen are grouped according to four main functions: Program, Amplifier, User Prefs, and Firmware settings. Program functions include loading and saving 16-channel parameter sets for later recall (LOAD, SAVE), determining which of the stored parameter sets will be initially loaded upon instrument boot-up (SET START-UP PROGRAM), and naming the instrument (INSTRUMENT NAME). Amplifier functions include setting the Common Reference type (REFERENCE), applying the Notch filter if necessary (NOTCH FILTER), determining required parameters for passing stimulating current through the instrument (STIMULATION INPUT), and generating a signal to be used to calibrate the amplifier or other instruments (CALIBRATION SIGNAL). User Prefs options include a variety of controls related to the LCD display (LCD SETTINGS), calibrating the touch-screen for a given user''s finger placement (CALIBRATE LCD), and determining the preferred STARTUP PAGE. Firmware options enable the user to identify which version of firmware and software is currently loaded on the instrument.


The Model 3500 is supplied with optional control software that runs on Windows® 2000 and Windows® XP. This software controls all features of the amplifier via a USB port (cable included).

The program also enables the storage of an unlimited number of 16-Channel parameter files, as well as provides a real-time notepad that logs changes in parameter settings or experimenter-added notations.